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Filtered Search Results
Medchemexpress LLC Argonaute-2 inhibitor BCI-137 | 112170-24-8 | MFCD05148320 | 98.9% | 313.29 | C11H11N3O6S | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BCI-137 is a small-molecule competitive inhibitor of Argonaute 2 (AGO2) that binds to residues in the MID domain. It is supplied for laboratory research and is provided as a solid or as a DMSO solution.
- Competitive AGO2 inhibition with a reported IC50 of 342 μM.
- Molecular weight 313.29 and formula C11H11N3O6S.
- Available as a solid (typical 10 mg) or as a 10 mM solution in DMSO.
- Storage stability: powder stable at -20°C for extended periods.
- Intended for research use only; not for human or veterinary applications.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Luxeptinib | 1616428-23-9 | 495.43 | 50 MG
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Luxeptinib (CG-806) is an orally active, reversible, first-in-class, non-covalent, and potent pan-FLT3/pan-BTK inhibitor. It has been shown to induce cell cycle arrest, apoptosis, or autophagy in acute myeloid leukemia cells. Luxeptinib also inhibits cell proliferation and suppresses BCR signaling-induced phosphorylation.
- Orally active, reversible, first-in-class, non-covalent, and potent pan-FLT3/pan-BTK inhibitor.
- Induces cell cycle arrest, apoptosis, or autophagy in acute myeloid leukemia cells.
- Inhibits cell proliferation with an IC50 of 32 nM in MEC-1 CLL cells.
- Suppresses BCR signaling-induced phosphorylation of BTK, PLCγ2, AKT, ERK1/2, and S6 ribosomal protein in primary chronic lymphocytic leukemia (CLL) cells.
- Completely inhibits phosphorylation of FLT3 and STAT5 in MV4-11 cells.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 1-Hexadecanol | 36653-82-4 | 99.8% | 1 ML
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1-Hexadecanol is a fatty alcohol and a lipophilic substrate, used for the research of ferroptosis.
- Increases the level of lipid peroxidation in HT1080 cells.
- Increases FAR1 KO HT1080 cells sensitivity to ferroptosis.
- Has no effect on RSL3-induced ferroptosis in HT1080 cells expressing GNPAT or AGPS shRNA.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Continentalic acid | 19889-23-7 | 10 MG
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Continentalic acid, isolated from Aralia continentalis, is a chemical compound primarily studied for its antibacterial properties. It is a white to off-white solid and is intended for research use only.
- Demonstrates minimum inhibitory concentrations (MICs) of 8-16 μg/mL against S. aureus
- Effective against Methicillin-susceptible Staphylococcus aureus (MSSA)
- Effective against Methicillin-resistant Staphylococcus aureus (MRSA) standard strains
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC ZY-444 | 1802650-31-2 | 99.5% | C26H28N4OS | 100 MG
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ZY-444 is an anti-cancer agent that targets pyruvate carboxylase (PC). It suppresses the Wnt/β-catenin/Snail signaling pathway by blocking the nuclear translocation of β-catenin. This compound selectively inhibits proliferation, migration, and invasion, and induces apoptosis in cancer cells. It has demonstrated potent anti-tumor effects in cancer mouse models and is suitable for the study of breast cancer, lung cancer (NSCLC), prostate cancer, and iodine-refractory thyroid cancer.
- Suppresses Wnt/β-catenin/Snail signaling pathway
- Inhibits proliferation, migration, and invasion in cancer cells
- Induces apoptosis in cancer cells
- Demonstrates anti-tumor effects in cancer mouse models
- Can be used for breast, lung, prostate, and thyroid cancer research
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Medchemexpress LLC SUVN-911 | 2414674-71-6 | 99.13% | 261.15 | 50 MG
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SUVN-911 | 2414674-71-6 | 99.13% | 261.15 | 50 MG
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Medchemexpress LLC Oleonuezhenide | 112693-21-7 | 5 MG
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Oleonuezhenide, isolated from Fructus Ligustri Lucidi, is a compound that exerts neuroprotective effects. It is provided as a white to off-white solid and is intended for research use only.
- Exhibits neuroprotective effects
- High purity of 99.27%
- Molecular formula: C48H64O27
- Molecular weight: 1073.01
- Soluble in ethanol (≥ 50 mg/mL)
- Provided with in vivo dissolution protocols
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Medchemexpress LLC Cytotoxic DNA minor groove interstrand crosslinking pyrrolobenzodiazepine dimer | 1595275-71-0 | MFCD34469130 | 98.9% | 584.66 g/mol | C33H36N4O6 | 5 MG
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SG3199 is a pyrrolobenzodiazepine (PBD) dimer that forms covalent DNA interstrand cross-links in the minor groove, producing potent cytotoxicity. It is used as the released warhead component of tesirine-based ADC payloads and as a research reagent for preclinical ADC and cytotoxicity studies. Supplied as a high-purity material with recommended low-temperature, light-protected storage.
- Potent DNA minor-groove interstrand crosslinker.
- Designed for ADC payload and preclinical cytotoxicity research.
- High purity (98.9%).
- Molecular weight 584.66 g/mol; formula C33H36N4O6.
- Storage: -20°C, protect from light, store under inert gas; in solvent: -80°C for extended storage.
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Medchemexpress LLC L-692429 (MK-0751) | 145455-23-8 | 99.9% | 509.60 | 10 MG
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L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. It binds to G protein-coupled receptor with a Ki of 63 nM. This product is for research use only.
- Stimulates intracellular calcium release, inositol phosphate (IP) turnover, cAMP-responsive element binding protein (CREB) activity, serum-responsive element activity, and bioluminescence resonance energy transfer (BRET) activity.
- Increases fluorescent emission in HeLa-T4 cells transiently expressing the flag epitope-tagged growth hormone secretagogue (GHS) receptor.
- Activates the GHS receptor, significantly increasing luciferase activity and suggesting stimulation of the MAPK pathway.
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eMolecules Neopentyl glycol mono(hydroxypivalate) | 1115-20-4 | MFCD00059597 | 5g
Combi-Blocks, Inc. | Neopentyl glycol mono(hydroxypivalate) | 5g | 603131375 | QC-3745 | 95.000 | 1115-20-4 | MFCD00059597 | 204.266 | C10H20O4
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eMolecules Monolaurin | 1G | Ships from Wood Dale, IL | Chem-Impex | 142-18-7 | MFCD00037815 | MW: 274.4
Chem-Impex | Monolaurin | 1G | 142-18-7 | MFCD10696649 | MW:268.441
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Medchemexpress LLC Isopropamide iodide | 71-81-8 | 98.0% | 5 MG
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Isopropamide iodide is a long-acting quaternary anticholinergic agent. It is used in the treatment of peptic ulcer and other gastrointestinal disorders characterized by hyperacidity and hypermotility.
- Long-acting anticholinergic agent
- Used for peptic ulcer treatment
- Addresses gastrointestinal disorders with hyperacidity
- Effective for gastrointestinal disorders with hypermotility
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eMolecules 1-Allyl-3-(2-hydroxyethyl)-2-thiourea | 105-81-7 | MFCD00002838 | 1g
Oakwood Chemical | 1-Allyl-3-(2-hydroxyethyl)-2-thiourea | 1g | 537676380 | 018162 | | 105-81-7 | MFCD00002838 | 160.240 | C6H12N2OS
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![eMolecules Medchem Express / BI-2545 / 5mg / 532149168 / HY-124772 / / 2162961-71-7 / [null] / 527.427 / C23H19F6N5O3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455880.PNG-250.jpg)
eMolecules Medchem Express / BI-2545 / 5mg / 532149168 / HY-124772 / / 2162961-71-7 / [null] / 527.427 / C23H19F6N5O3
Medchem Express / BI-2545 / 5mg / 532149168 / HY-124772 / / 2162961-71-7 / [null] / 527.427 / C23H19F6N5O3
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Sigma Aldrich Fine Chemicals Biosciences 3-Methyl-2-buten-1-ol >=98%, FG | 556-82-1 | MFCD00002916 | 1KG
3-Methyl-2-buten-1-ol >=98%, FG | Purity: >=98% | Mol Wt: 86.13 | 556-82-1 | MFCD00002916 | 1KG
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